Reference number
ISO 20776-1:2019
International Standard
ISO 20776-1:2019
Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices — Part 1: Broth micro-dilution reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases
Edition 2
2019-06
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ISO 20776-1:2019
70464
Published (Edition 2, 2019)

ISO 20776-1:2019

ISO 20776-1:2019
70464
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Format
CHF 129
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Abstract

This document describes one reference method, broth micro-dilution, for determination of MICs. The MIC can be a guide for the clinician, and reflects the activity of the drug under the described test conditions, by taking into account other factors, such as drug pharmacology, pharmacokinetics, or bacterial resistance mechanisms. This allows categorisation of bacteria as "susceptible" (S), "intermediate" (I), or "resistant" (R). In addition, MIC distributions can be used to define wild type or non-wild type bacterial populations. Although clinical interpretation of the MIC value is beyond the scope of this document, modifications of the basic method are required for certain antimicrobial agent - bacteria combinations to facilitate clinical interpretation. These modifications are included in a separate annex of this document. It is necessary to compare other susceptibility testing methods (e.g. disc diffusion or diagnostic test devices) with this reference method for validation, in order to ensure comparable and reliable results.

General information

  •  : Published
     : 2019-06
     : 2019-12
     : 2019-12
    : Close of review [90.60]
  •  : 2
     : 19
  • ISO/TC 212
    11.100.20 
  • RSS updates

Sustainable Development Goals

This standard contributes to the following Sustainable Development Goal

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